Myalgia and Myositis

Fibromyalgia and Diffuse Myalgia

Chronic pain is one of the most common complaints encountered by primary care clinicians. Often, patients present not with well localized pain but with diffuse and nonspecific myalgias. Fibromyalgia is the most common etiology for this type of pain. In community-based studies, 2% [1] and 1.2% to 6.2% of school-age children screened positive for fibromyalgia [2–4]. Women and girls are at higher ...

Internalised capillaries, neuromyopathy and myalgia.

Internalised capillaries are described in the muscle fibres of two adult males who complained of exertional myalgia. In one patient, "bundles" of internalised capillaries were found in 2% of the Type 1 fibres and many of the Type 1 fibres exhibited non-specific cytoarchitectural changes. The other had hereditary motor and sensory neuropathy (HMSN) Type 2 and his muscle biopsy exhibited the more...

PMS and eosinophilia-myalgia syndrome.

Low serum 25 (OH) vitamin D levels (<32 ng/mL) are associated with reversible myositis-myalgia in statin-treated patients.

Our specific aims were to determine whether low serum 25 (OH) vitamin D (D2 + D3) (<32 ng/mL) was associated with myalgia in statin-treated patients and whether the myalgia could be reversed by vitamin D supplementation while continuing statins. After excluding subjects who took corticosteroids or supplemental vitamin D, serum 25 (OH) D was measured in 621 statin-treated patients, which consist...

[Eosinophilia-myalgia syndrome].

The following is an outline of one typical case of chronic eosinophilia-myalgia syndrome (EMS). In 1987 a 62-year-old woman began taking L-tryptophan, 1.5 g nightly, due to sleeping difficulty. During the months preceding the appearance of EMS she continued to take L-tryptophan, derived from the biosynthetic production of the Japanese manufacturer "Showa Denko". She has suffered increasingly fr...